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Introduction to Proper and Scientific Integration Techniques for Chromatographic Systems


Course Description:

The complexity of environmental chromatography, both organic and inorganic, has raised a number of serious issues in the generation of data. One issue that has caused significant difficulty centers on the proper set up of instrument integration parameters and the use of manual integration techniques. In an open letter to environmental laboratories dated September 5, 2002, the EPA-OIG expressed a strong concern regarding the misuse of manual integration techniques to bypass quality control requirements. It has, therefore, become increasingly important for analysts and data reviewers to be well versed in the techniques of quantification and integration of complex chromatographic analyses. Additionally, having a chromatographic system that is properly optimized minimizes the need for manual integration, extra effort, and documentation, and increases productivity.

This webcast will focus on the fundamental issues of automated and manual integration techniques, emphasizing proper technical requirements for sound integration, optimizing chromatography, proper documentation of manual integrations, and problems associated with improper integration techniques. The class will use interactive discussions, presentations, and live data examples with problem solving techniques to demonstrate proper techniques and processes in relation to chromatography, published methods, and meeting the TNI Standard requirements. Chromatographic analysis principles considered in this training include those applicable to GC, GC/MS, HPLC, and ion chromatography. This information and the specific techniques applicable to environmental samples are not generally taught in most secondary schools, by instrument vendors, or in-house. Presentations and discussions will focus on when and how to properly manually correct integrations to assure the integrations are accurate, reproducible, consistent, and representative of the response.

Expected Learning Outcomes:

  • Understand why this is an important issue for laboratories and the industry
  • Explore the fundamentals of peak detection, instrument integration, and chromatographic software systems
  • Learn how to optimize the integration parameters of a chromatographic system
  • Learn how to optimize chromatographic conditions using live data
  • Real life integration problems that challenge analysts on a daily basis
  • Manual integration basics and the need for manual integration activities
  • Documentation requirements for manual integrations
  • Examples of improper manual integrations
  • Tips on what to include in a Manual Integration SOP

Intended Audience:

This course is designed for Managers, Supervisors, Analysts, Quality Assurance Staff, Laboratrory Auditors and Assessors, and Data Validators.

$180 for TNI members
$195 for non-members

TNI Members: you must be logged-in to the website to receive the member rate.

No certificates are automatically provided with this training. A Certificate of Completion (CoC) ($30 per person) or Certificate of Attendance (CoA) ($20 per person) may be purchased during or after registration or webcast purchase. A passing score of at least 70% must be received on the exam in order to receive CEUs and a CoC. Scores of less than 70% will receive a Certificate of Attendance at no reduced fee. For a CoA you will not need to take the quiz and you will not receive CEUs. To receive your certificate, contact Paul Junio at [email protected] with date of purchase and date of training completion. See FAQs for additional information.


About Webcasts: Upon receipt of your payment, you will receive a special link by e-mail to watch the webcast on your computer. The link is time-limited: you will have full access to the webcast and any associated handouts for 6 months after receipt of payment, at which time the link will expire. Webcasts cannot be downloaded; they are intended for viewing on your computer only during the 6-month window. If you have any questions, please contact Ilona Taunton at [email protected].

4 hours

CEUs: 0.4

Presented By:

Jack Farrell

About the Presenter:

Jack Farrell has more than 40 years of experience in the environmental industry as an analyst, QA professional, technical and general manager of small, medium and large commercial laboratories. He is an experienced environmental manager, laboratory chemist, trainer, and auditor. Mr. Farrell holds degrees in Biological Sciences (Microbiology) and Chemistry and is a professional trainer, consultant and third party assessor for a number of state and federal regulators.

Jack Farrell is a Senior Environmental Analyst, President and Founder of Analytical Excellence, Inc. (AEX). Since its inception in 1993, AEX has been an independent strictly confidential consulting firm specializing in environmental laboratory operations, analysis and matters concerning the generation of analytical data to support effective compliance decision-making and aspects of litigation. AEX's clientele consist of well-known small and large laboratory companies, instrument manufacturers, engineering firms, state and federal regulatory agencies and legal practice firms.